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As the authors point out, these findings may help to explain why these metabolic abnormalities occur in a cluster (such as found in the metabolic syndrome), partly because people are exposed to low doses of various POPs simultaneously

High-Performance Liquid Chromatography (HPLC) HPLC is the gold standard for testing glutathione

A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism

CBS C699T and ammonia For a very good overview on CBS up-regulation via C699T (the gene with the most data), take a look at this article by Mark London at MIT

They promote zinc entry into the lumens of subcellular compartments, where it is required (for zinc proteins, e.g., zinc-containing enzymes (246)