glutathione trapping assay of reactive drug metabolites produced by biomimetic metalloporphyrin catalysts - Lassila - 2015 - Rapid Communications in Mass Spectrometry GSH trapping incubations in HLMs

During a copper-deficient state, the copper deficiency leads to mitochondrial dysfunction and ROS accumulation, which in-turn lead to cardiovascular diseases including myocardial I/R injury (94)

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Similarly, 6-gingerol suffers from poor water solubility, instability in physiological fluids, and rapid metabolism, all contributing to low oral bioavailability (224)

The inclusion criteria stipulated that participants be healthy male and female non-smokers, aged 30-79 years, who had not taken antioxidant supplements for at least one month prior to enrollment

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