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However, paradoxically, excessive Fe accumulation can trigger intracellular iron overload, promoting ferroptosis

10.1016/j.jtcvs.2013.09.060 86

Asiatic acid, extracted from Centella asiatica and induces apoptosis pathway through the phosphorylation p38 mitogen-activated protein kinase in cisplatin-resistant nasopharyngeal carcinoma cells