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Description

DOI: 10.1007/0-306-46870-0_10

Your skin feels chronically dry on the inside ( Sok-geonjo ), yet looks shiny or oily on the surface

However, with aging, the efficacy of key UPRER regulators such as PERK, IRE1, ATF6, among others, diminishes, leading to challenges in ER stress mitigation and an increased susceptibility to pathological UPRER activation [326,327,328]