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In addition, the challenges encountered in the preclinical experimental stage and clinical translation of ferroptosis inhibitors are summarised

Landmon CA, Davies C, Pape SM, Bassett SE, McCann JD

Conversely, functional studies confirm that the GSTM1 null genotype directly reduces detoxification capacity, providing mechanistic evidence for causality [271,272]

PMID: 14500347

Xiang, K, Wang, E, Mantyh, J, Rupprecht, G, Negrete, M, Sanati, G, Hsu, C, Randon, PM, Dohlman, AB, Kretzschmar, K, Bose, S, Giroux, N, Ding, S, Wang, L, Balcazar, JP, Huang, Q, Sundaramoorthy, P, Xi, R, McCall, S, Wang, Z, Jiang, C, Kang, Y, Kopetz, S , Crawford, G, Lipkin, SM, Wang, XF, Clevers, H, Hsu, D, Shen, X