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4), a patient exhibiting clinical symptoms of cholestatic disease with no known cause should undergo genetic testing to look for mutations in the known genes that cause cholestasis [19]

Mellidou et al., 2012)

Several studies have explored the efficacy of Thiamidol in treating melasma & other hyperpigmentation conditions

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Sakurai T, Miyazawa S, Hashimoto T (1978) Effects of di-(2-ethylhexyl) phthalate administration on carbohydrate and fatty acid metabolism in rat liver