glutathione redoxin Glutaredoxin - an overview Glutathione redox cycle. Glutathione (GSH)

Stop the damage

When Sxc-is abolished in animal models, behaviors such as approaching foods on cue even when punished, perseverative errors and cocaine-primed drug seeking are increasingly present (Hess et al., 2023)

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Cell lines The RAW264.7 murine macrophages (ATCC TIB-71 TM ), THP-1 human monocyte (ATCC TIB-202 TM ), U937 human leukaemia (ATCC CRL-3253 TM ), A549 human epithelium (ATCCCCL-185), and BEAS-2B human bronchial epithelium (ATCC CRL-3588 TM ) cell lines were grown in Dulbeccos Modified Eagle (DMEM) or Roswell Park Memorial Institute (RPMI)-1640 medium supplemented with 10% foetal bovine serum (FBS) and 1% penicillin/streptomycin (PS) (Gibco, Texas, USA), followed by incubation at 37 C in a 5% CO 2 incubator

Esta alteracin se acompaa de un aumento de la produccin de citoquinas, como el factor de necrosis tumoral (TNF-), y las interleuquinas IL-1, IL-6 e IL-8