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doi: 10.1111/jpi.12559 31 LombardoFGiorginiEGioacchiniGMaradonnaFFerrarisPCarnevaliO

Data synthesis The studies varied in terms intervention type, dosage regimens, duration of treatment, study design, and participant characteristics such as disease stage and concurrent medication hence given the substantial heterogeneity, a quantitative meta-analysis was not performed

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However, in the study conducted by Huiya Li et al., cell debris generated through the repeated freezethaw cycles of HT22 cell lines in the OGD/R model inadequately represented the substantial quantity of myelin debris produced following ischemic injury

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