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Metagenomic and metabolomic studies have shown that in humans and mice with insulin resistance, microbial pathways involved in the breakdown of complex carbohydrates (trehalose, maltose, fructose) are enriched

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Additionally, non-P-selectin interactions between platelets and the endothelium, involving glycoprotein IIb/IIIa binding to endothelial ICAM-1 and fibrinogen cross-linking, were described (74)