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The ex vivo fluorescence imaging of organs and the tumor taken from 5 h post-injection similarly showed that the intensity of the fluorescence signal of the tumor was more than ten times higher than that of other organs, such as the liver and kidney (Fig

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Interestingly, DBD-treated GSH and GSSG samples showed a similar response in terms of prominent Raman bands: While GSH is converted to GSSG during short treatment times, GSSG appears only as an intermediate product during plasma-induced modification processes

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Such sensitivity to ferroptosis can be considered the foundation of pharmaceutical development for killing HLRCC cells selectively in the future