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Collectively, the above referred evidence supported the notion that inducing ferroptosis greatly contributed to hepatic steatosis in NASH/NAFLD by facilitating hepatic lipogenesis and abnormal lipid accumulation in the liver

FIGURE 5 Lapatinib Inhibits Neuronal Ferroptosis by Maintaining Glutathione Peroxidase 4 Next, we probed the molecular mechanism of lapatinibs neuroprotection against neuronal ferroptosis

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