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En particular, la glutatin reductasa pareciera ser una buena diana teraputica para la accin de antimalricos, ya que la glutatin reductasa del parsito Plasmodium falciparum es significativamente diferente en cuanto a estructura y plegamiento a la glutatin reductasa de los mamferos

Furthermore, we show that targeting mitochondrial metabolism, particularly by inhibiting Complex I, sensitizes CRC cells to 5FU, resulting in delayed tumour growth and prolonged survival in preclinical models

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