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BioMed Res Int 2014:151479

Drug Class Review: Nonsteroidal Antiinflammatory Drugs (NSAIDs): Final Update 4 Report

We found that while HGF or c-MET inhibition alone had variable effects on cancer migration, stemness and EMT, simultaneous inhibition of both the ligand and receptor (Hi + Ci) consistently reduced cancer cell migration/invasion into collagenous matrices, stem cell marker expression and EMT (Fig