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Murine studies have demonstrated the existence of a link between vigorous anti-infectious responses and propensity to develop autoimmune diseases (108)

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38 (International Pediatric Research Foundation, Inc, 1995)

[242], it was observed that pretreatment with antibiotics successfully eradicated a significant portion of the intestinal microbiota found in the feces of mice, thereby replicating the GI conditions observed in germ-free mice