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mTORC1 activity sustains high levels of aerobic glycolysis in T E cells, and inhibition of mTORC1 activity reduces glucose uptake and lactate production in IL-2-maintained T E cells [80]

The demographic, health behavioral, and clinical characteristics of the study population are summarized in Table 1

It offers ASD evaluations through a pediatric department staffed by internationally trained, English-speaking sub-specialists

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Like other sulfhydryl compounds, amifostine is thought to work primarily via free radical scavenging and up regulation of existing enzymes superoxide dismutase and glutathione peroxidase [50], however, some authors have proposed it may work via a p53-dependent mechanism [55]