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10.1016/j.ijid.2020.05.065 225 WangW.WangJ.DongS.-F.LiuC.-H.ItalianiP.SunS.-H.et al (2010)

After chromatographic separation the hydroxy groups in (2 R ,3 R )- 50 were protected as silyl ethers to allow oxidation at C5 to produce pyrrolidine-2-one (4 R ,5 R )- 47 (Scheme 12) which was later transformed into (2 S ,3 R )- 34 as already shown (Scheme 11) [61]

Lund, T., A

This means it is an important lead drug that can be used to optimize reversing drug resistance in fungal ABC systems, especially azole resistance in Candida ( Results of an investigation using two antibodies and specific pump inhibitors in 18 C

They are commonly found in jet fuels as well as some pharmacologic agents and in monomethylhydrazine containing mushrooms such as Gyromitra esculenta (false morel)