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Several oncogene activating mutations play an important role in promoting colorectal cancer

Recently, a strong reduction of the mitochondrial potential was also reported in cuprizone-treated oligodendrocytes in vitro (Benardais et al., 2008

Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer

Clinical studies in non-diabetic cohorts have demonstrated modest vascular and myocardial improvements, but findings remain variable and definitive cardiovascular outcomes trials are still lacking (Lexis et al., 2014