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10.1164/ajrccm.163.2.2001038 66

The difference in specific activity between CuZnHis(L) and CuHis(L) assemblies is mainly attributed to the difference in specific surface area and, therefore, the number of exposed catalytic sites

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Notably, several agents have received regulatory approval in the US, China, and the EU, while others are advancing through Phase II and III trials

When administered subcutaneously (just under the skin) or intramuscularly (into the muscle), the peptide enters the bloodstream more directly, bypassing the digestive system entirely