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Disclosures: Chip Bowman: Nothing to Disclose, Elizabeth Verna: Nothing to Disclose 1762 OPTIMAL TREATMENT DURATION OF RESMETIROM FOR METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE: A COST-EFFECTIVENESS ANALYSIS Phuc Le 1 William Herman 2 Srinivasan Dasarathy 1 Wen Ye 3 Victoria Criswell 1 Nicole Welch 1 Michael Rothberg 1 , 1 Cleveland Clinic, 2 University of Michigan at Ann Arbor Medical School, 3 University of Michigan at Ann Arbor School of Public Health Background: With recent approval from the US Food and Drug Administration, resmetirom is the first pharmacotherapy for metabolic dysfunction-associated steatohepatitis (MASH) and significant fibrosis (F2-F3)

The compound remains detectable in urine for up to 4 days by mass spectrometry methods, despite its short plasma half-life, suggesting tissue distribution and binding may extend its biological effects beyond plasma clearance times

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[DOI] [PMC free article] [PubMed] [Google Scholar] 380.Gil Rosa B, Akingbade OE, Guo X, Gonzalez-Macia L, Crone MA, Cameron LP, Freemont P, Choy K-L, Gder F, Yeatman E, Sharp DJ and Li B, Biosens

Airborne microplastics: consequences to human health