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Particularly, Hg, Cd, and Pb levels exceeded the respective critical values 1.02, 0.30 and 0.25 g/wet weight (that is, the legal safety limits established by the European Community) in eight, three, and two of the swordfish specimens examined, respectively

Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl deficient cystathionine -synthase heterozygous mice

it also lowered ROS levels by stimulating the Nrf2/HO-1 axis and maintained epithelial barrier stability by upregulating E-cadherin and Occludin

Beyond that, peptide concentration drops below therapeutic threshold (typically defined as 80% of initial concentration in pharmaceutical stability testing)