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The degradation of the BBB in AD pathology is one of the causes of neuroinflammation and results in the activation of downstream cascades associated with neural injury and neurodegeneration (Sweeney et al., 2018)

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity

Further, its adducts are concentrated in A plaques with mutual correlation (Figure 2D

Footnotes 1.^ 3.^ 4.^ 5.^ 6.^ References 1 AverbukhL

Scavenging ROS and regenerating other antioxidants like vitamin E and glutathione are some of its main functions (Rezayian et al., 2019)