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11 Transcription factors are a class of protein which bind to DNA and induce the expression of particular genes, in the case of Nrf2, the pathway stimulates the production of potent antioxidants such as: NAD(P)H:quinone oxidoreductase 1 (NQO1) and glutathione S-transferases (GSTs), and many others, as shown in the table below

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Review Article OPEN ACCESS Author information Abstract Hepatocellular carcinoma (HCC) is one of the most common and highly heterogeneous malignancies worldwide