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Sandborn WJ, van Assche G, Reinisch W, Colombel J-F, D'Haens G, Wolf DC, Kron M, Tighe MB, Lazar A, Thakkar RB

doi: 10.1038/nrendo.2014.60 131 MazidiMde CaravattoPPSpeakmanJRCohenRV

NSAIDs have been found to impact glutathione levels in several ways: Increased Demand for Detoxification: NSAIDs are metabolized primarily in the liver, where they undergo biotransformation before being excreted