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But when theres a lack of DAO, a DAO deficiency, histamine can assist in creating intestinal permeability and upregulated inflammation

As the principal selenium transporter in the brain, SELENOP crosses the BBB via endocytosis by brain endothelial cells [108]

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Finally, while our results consistently demonstrate that Se/LDH@PEG-M modulates the macrophage population by suppressing M1 markers and enhancing M2 traits, it remains to be definitively verified whether this represents a direct phenotypic reprogramming of existing M1 macrophages into M2 macrophages

This molecular-level design strategy effectively overcomes the inherent limitations of conventional static biomaterials (Table 3)