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Oxidative stress in RA overloads the UPS, leading to the accumulation of ubiquitin conjugates and exacerbating cellular damage and inflammation

4 Antimicrobial activities of AgNPs AgNPs have demonstrated potent antimicrobial effects against a wide range of pathogenic microorganisms, including both Gram-positive and Gram-negative bacteria, as well as fungi ( Table 1 )

Cushingoid features, growth retardation, increased risk for infections), and suppression of the hypothalamic-pituitary-adrenal (HPA) axis, which can result in an adrenal crisis if doses are not carefully tapered after a patient has been on systemic steroids for more than 15 days (Aljebab et al, 2017)

During this process, you also create byproducts, including free radicals

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