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Randomised, double blind, placebo-controlled study of Bronchitol (inhaled dry powder mannitol) in cystic fibrosis [abstract]

42 The cold stress-mediated activation of the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1)-MAPK14/p38 pathway also suppresses erastin- and RSL3-induced cell death

This patient was identified to have a presumed de novo variant of COL3A1 p.Glu1171Lys and was published in 2015 by Frank et al

HHMI International Fellow (S.P.)

When the staining workflow was resumed the following day, cells were permeabilized with BD Perm/Wash buffer for 15 min prior to being stained for 30 min at RT with anti-IL-17A (BioLegend, clone TC11-18H10.1, Cat