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Hence, combining treatments depending on the period of biofilm formation described in this review will be necessary to eradicate the biofilm utterly

Sabzevari, Biol

Most of these antitumor effects are mediated by directly targeting FOXM1, but some are not

Zinc supports this interplay by maintaining antioxidant enzymes, including peroxisomal Cu/Zn-SOD and mitochondrial SOD1, and by regulating redox signaling pathways 97

Current research has significantly explored the bidirectional relationship between dysregulated brain metabolism and sleep impairments in influencing aging as well as age-associated neurocognitive deficits, and suggests that alterations in any one of them exacerbate the other, leading to accelerated aging and neurodegeneration ( vice versa , since impaired glucose utilization, lipid metabolism as well as oxidative stress in the mitochondria, are altered as we age and conversely, exacerbated ROS and a decline in bioenergetics in neuroglial cells, aggravates aging and cognition (Bratic and Larsson, 2013