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These findings strongly suggest that nanoparticles modified with cell-penetrating peptides possess a destructive effect on ZO-1, potentially enhancing corneal permeability through the paracellular pathway

It remains unclear whether this negative association is due to -cell lipotoxicity or the adverse effects of elevated FFA concentrations on hepatic and peripheral tissue insulin sensitivity

designed Ce-sH nanoparticles for the treatment of alkaline corneal burns, with the goal of enhancing Statens Seruminstitut Rabbit Cornea (SIRC) cell proliferation through insulin-like growth factor 1 (IGF-1) [20]

This clinic also provides injections of hemin for the treatment of acute intermittent porphyria