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In brown adipose tissue and skeletal muscle, TGR5 induces type 2 deiodinase (DIO2) expression, converting thyroid hormone T4 to T3 and stimulating mitochondrial energy metabolism (75)

A., Downey, A., Mudra, D., Krueger, L., Carroll, K., Chengelis, C., Madan, A., and Parkinson, A

By comparing reconstructed 3D volumes of each cluster, the particle stacks representing distinct states were identified and subsequently subjected into the non-uniform consensus refinement and the receptor-focused refinement