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A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity

For oral administration, clinical trials have studied doses ranging from 1-30 mg daily, with typical protocols using 1-2 mg per dose on an empty stomach

While nearly all this research involves animal models, the consistency of results across different injury types and body systems has generated significant interest in the peptide therapy community

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