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While the exact cause of PCOS is not fully understood, it is believed to involve a combination of genetic and environmental factors

3A, E, F and Supplementary Fig

Piccoli et al., 2008)

doi: 10.1074/jbc.274.36.25481 45 JhangK

Increased oxidative stress induces high ROS levels and diminishes the interaction between KEAP1 and PGAM5, a mitochondrial serinethreonine phosphatase [74, 160]