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There is mounting evidence that elevated plasma homocysteine (and therefore decreased serum methionine) contributes to congenital neural tube defects

L.GuthrieK

It also helps patients understand an important point: no matter which healing system they explore, safe care must remain evidence-based, supervised, and individualized

It also provides support to the neurological system

Early initiation of folic acid supplementation (210 mg/kg/day) is recommended, and patients who begin supplementation before the age of 6 years tend to have a better prognosis than those who start supplementation after the age of 6 years [101]