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With special reference to the novel mitochondrial disorder we have described in the CESLAC patients, several lines of research suggest that the ketogenic diet may be particularly useful for complex I defects (229, 230)

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Der Rohstoff wird in einem chemisch-synthetischen Prozess aus Epichlorhydrin, Trimethylamin und Essigsure gewonnen

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however, mipomersen is unfortunately no longer available for clinical use, due to critical adverse effect of hepatotoxicity