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The absorption spectra clearly suggest that TPE-DCV can react with GSH, Cys and Hcy through thiol-ene click reaction to form thioether (Figure S5)

Lednicer, The Organic Chemistry of Drug Synthesis , Volume 7, J

However, the quantities of these enzymes vary under conditions of high OS, such as sepsis, which may lead to an accumulation of harmful ROS (Andrades et al., 2005)