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Thus, we analyze how organisms, ranging from single cells to humans, respond to various forms of hypoxia and how these responses influence regenerative processes with significant biomedical implications

These changes are consistent with known metabolic effects of ketogenic diets, including reduced insulin signaling, increased reliance on fatty acid oxidation, and enhanced utilization of BCAAs [37, 38]

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In response, the endothelial cells at the leading edge of capillary growth are converted into tip cells, which are highly proliferative and can migrate towards the angiogenic signals (36,37)

J Biol Chem 301:110571 Artuc M, Bohm M, Grutzkau A, Smorodchenko A, Zuberbier T, Luger T, Henz BM (2006) Human mast cells in the neurohormonal network: expression of Pomc, detection of precursor proteases, and evidence for Ige-dependent secretion of alpha-Msh