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Blood biochemical indicators, including liver and kidney function tests, blood lipid levels, and blood glucose, should be monitored every three to six months

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As a byproduct of amplified TCR activation, T cells shift toward an effector phenotype, the key subset responsible for tumor killing (80, 81)

Vincristine was shown to induce apoptosis in interphase cells of mouse small intestinal crypts (59), and cisplatin increases apoptosis not only in proliferating crypt cells but also in differentiated villus enterocytes in the jejunum by 2.3-fold (94)

Raynauds disease Approximately 85 percent to 95 percent of systemic sclerosis patients experience Raynauds disease, according to the Cleveland Clinic