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The flys nervous system shares significant functional and structural similarities with mammals, making it an ideal model for studying the molecular pathways underlying AD pathology

cell transformation, genome instability, hyperproliferation, immortalization, angiogenesis, epithelial-mesenchymal transition (EMT) and metastasis, which are all influenced in several ways by intracellular ROS 48,49

Given that dietary vitamin E restriction has limited therapeutic potential in cancers, the authors sought to identify molecular mechanisms underlying vitamin E uptake by cancer cells

Barger et al

Utilizing high-throughput measurement methods applied to the novel, more accurate and appropriate model systems will provide valuable data for the development of GSH metabolism and interaction models both as mechanistic, knowledge-based or machine-learning, data-based models providing platforms for drug target determination and investigation of complete effect of combined therapies