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Concomitantly, metabolomic analysis showed significant differences between aged WT and Mda5 -/- HSCs

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This engineering was necessary to reduce the proliferative effect of native FGF19 on hepatocytes, mediated via signaling through FGFR4the only FGF receptor at which FGF19 and FGF21 differ in agonist activity (305)

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Torres-Ramos YD et al

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PubMed Central PMCID: PMC5877694

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