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HIF-1 induces metastasis, which is the primary cause of tumor-related deaths (Wong et al., 2011)

10.1111/j.1471-4159.2005.03014.x J

China 2 , 303308 (2008)

[Article] [PubMed]13

By use of cultured immortalized podocytes and mouse models, they could demonstrate that GH excess activates Notch1 signaling in podocytes resulting in podocyte loss