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Advanced Glycation End Products Obstruct Skin Wound Healing Diabetes patients produce more glycation end products than non-diabetic individuals and often suffer from foot ulcer complications

Macrophages can polarize into pro-inflammatory M1 or anti-inflammatory M2 phenotype (Murray, 2017), and an imbalance in macrophage M1/M2 polarization contributes to various diseases or inflammatory conditions (Murray, 2017)

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doi: 10.1038/s41522-023-00462-9 165 QuR.LiM.LiP.SongY.DongB.LiuJ.et al

Reduced glutathione (L-glutathione) is the biologically active form naturally produced by the body