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However, sections from mice administered with PI3K inhibitor along with Tozasertib and ICV STZ revealed neutrophilic infiltration, decrease in the number of pyramidal cells and deposits of amyloid plaques (Fig

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This regulatory effect of DMF was identified through NRF2-dependent and independent mechanisms with NRF2 binding to ARE motifs and increasing DNA 5hmC of individual gene regulatory regions involved in the TSS pathway, cystine uptake, and GSH generation

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