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Single-cell RNA-seq data processing and analysis Obtain the gene-cell matrix of dataset CNP0001102 and use the R package Seurat to perform Unsupervised clustering Cell clustering

To investigate mechanisms underlying FTLD-GRN, single-cell transcriptomics in the thalamus and frontal cortex of Grn / mice and FTLD-GRN patients identified a conserved astrocytic pathology marked by upregulation of GJA1, AQP4 , and Apoe , and downregulation of the glutamate transporter SLC1A2

The simultaneous administration of curcumin and piperine to humans or animals boosted the serum levels by more than a thousandfold (51)

doi: 10.1039/d2np00036a 479 ZhangC

Vaginally delivered infants typically develop a gut microbiota that closely mirrors the maternal vaginal flora (205)