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It can be obtained by diet, the endogenous reserve known as glycogen or synthesized via gluconeogenesis ( As previously mentioned, cancer cachexia is a syndrome that alters the patients functional status and is characterized by loss of body fat, muscle mass, appetite and systemic inflammation

If undiagnosed, the disorder can lead to metabolic collapse, coma and even death

The metabolic effect of inadequate thyroid hormone is partly to blame

Its required for the breakdown of body fat, as well