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Lingvay et al., 2025) plus the Phase 1b pharmacodynamic data (Enebo et al., 2021)

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Mass spectrometry analysis revealed proteins with high homology to cancer cell antigens in the ~ 27/28 kDa band, leading to an antitumor immune response [41]

Homogeneity of variances across groups was checked by Levenes and Bartlett tests

Cognitive impairment, defined as an intermediate stage between the normal aging process and the onset of dementia, has a multifaceted etiology but specifically in the setting of metabolic disorders is sustained by a spectrum of factors, prominently featuring IR, lipotoxicity, and vascular-systemic inflammation, which are also shared with MASLD