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The absence of verified pharmacokinetics and product verification prevents evidence-based recommendations regarding discontinuation timing, perioperative safety, and postoperative resumption, leaving surgeons unable to quantify risk in elective operative settings

Mild side effects: Nausea, headache, and mild allergic reactions such as itching or rash

Rare but serious problems can happen, and some medicines might not work right with B12 shots

Subcutaneous (SC) Injection Less common for B12, but sometimes used

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