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doi: 10.1073/pnas.95.22.13217

4-hydroxy-2-nonenal (4-HNE), a toxic byproduct of fatty acid peroxidation, stimulates macrophages to trigger inflammation and AD progression, detectable across all AD stages (Renuka Sanotra et al., 2022

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In addition, they play a role in dominant follicle selection, as regressing follicles undergo a process of apoptosis which is promoted by ROS

Compared to traditional imaging methods, PET offers unique advantages in studying cellular metabolism, including higher spatial resolution and sensitivity