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Main limitation: synergy is shown for GHRH + secretagogue classes in general, not for this exact blend in a human trial

Surgery for spinal stenosis should be considered only after other conservative therapies have been exhausted because it is usually not as successful as hoped and leads to a new diagnosis failed back surgery syndrome, where symptoms continue to deteriorate

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Xeomin, for instance, is often recommended with a 1:1 dilution (e.g., 100 units with 1mL for 10 units per 0.1mL), similar to Botox