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Potential drug interactions also warrant attention, as probiotics may alter the pharmacokinetics or efficacy of immunosuppressive therapies, thereby increasing infection risk or compromising therapeutic outcomes, posing particular concerns for patients undergoing chemotherapy, organ transplant recipients, and individuals with HIV/AIDS

This indicates that mechanisms may not be directly linked to weight changes (Yang et al., 2016[165])

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4-hydroxynonenal-mediated signaling and aging