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doi: 10.1136/gutjnl-2020-323020 105 ZuoTZhanHZhangFLiuQTsoEYKLuiGCYet al

Homocysteine and Methylmalonic acid tend to start to rise when the B12 level is below 400pmol/L, so our Naturopathic doctors usually aim for the B12 to be well above 500 pmol/L

However, although our genetically engineered mouse model of RMC reproduces the aggressive and metastatic phenotypes observed clinically, there is no perfect equivalence between mouse models and human diseases, and thus, caution must be exercised when extrapolating these findings to the clinic

In medicine, tyrosinase is a key therapeutic target for treating a range of skin pigmentation disorders, including vitiligo 17 , hyperpigmentary 18,19,20,21 , and melanoma 22

accordingly with inflammatory bowel disease, cysteamine damaging effect particularly includes both upper and lower GI tract lesions (5-7, 9) may evidence BPC 157 effectiveness as a comparative link in both diseases