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Instead, they step up the treatment by adding other conventional DMARDs (like sulfasalazine or hydroxychloroquine) or biologic agents (like TNF inhibitors) directly to the existing MTX regimen to achieve tighter disease control (Cohen & Mikuls, 2025)

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B.JiaJ.ShiQiYangC.et al (2020)

Other factors that are implicated in the pathogenesis of glaucoma include vascular issues (leading to reduced blood flow to the optic nerve), mitochondrial dysfunction, excitotoxicity, and oxidative stress [70]